[Heat Nation] “Wade finally says, ‘What’s up, Bobby?’’’ the NBA source said. “Bobby laid into him, saying, ‘You might be a better player, but don’t ever challenge my work ethic.’ He accused Wade of not working hard enough by not practicing.”

This was during the Jimmy/Wade/Rondo season for the Bulls, when Jimmy and Wade called out the young guys for not working hard enough. Wade wasn't even practicing with the team at the time so Bobby called him out after staring him down with the crazy eyes.

Source: https://heatnation.com/rumors/bobby-portis-challenged-dwyane-wade-chicago/